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NEWS新聞資訊

Agrisera表觀遺傳學(xué)相關(guān)抗體促銷開始啦!

表觀遺傳學(xué)是指基于非基因序列改變所致基因表達水平變化。表觀遺傳的現(xiàn)象目前已知的包括DNA甲基化、基因組印記、母體效應(yīng)、基因沉默、核仁顯性、休眠轉(zhuǎn)座子激活和RNA編輯等。

其中組蛋白(Histone)的修飾作用是表觀遺傳學(xué)研究的一個重要領(lǐng)域。Histone H3與H2A、H2B和H4一起參與真核細胞中染色質(zhì)的結(jié)構(gòu)。組蛋白H3通過承受幾種不同類型的表觀遺傳修飾,參與并影響許多細胞進程,如轉(zhuǎn)錄激活/失活、染色體包裝、DNA損傷/修復(fù)。這些修飾,包括甲基化、瓜氨化、乙?;⒘姿峄?、小泛素相關(guān)修飾化、泛素化及二磷酸腺苷核糖基化。主要發(fā)生在組蛋白H3的N末端尾區(qū)域上,這導(dǎo)致核小體結(jié)構(gòu)重構(gòu)成更容易接近的開放構(gòu)象的轉(zhuǎn)錄復(fù)合物。在大多數(shù)物種中,組蛋白H3主要在賴氨酸9,14,18,23和56處乙酰化; 在賴氨酸4,9,27,36和79處甲基化; 并分別在ser10,ser28,Thr3和Thr11磷酸化。組蛋白修飾的深入研究能更好地了解細胞過程的表觀遺傳調(diào)控。


 

 

 

 

西美杰為您整理并推薦Agrisera公司經(jīng)過驗證的,高質(zhì)量的組蛋白表觀遺傳修飾抗體,產(chǎn)品如下:

產(chǎn)品名稱

貨號

適用物種

產(chǎn)品詳情

H3K18me1 | Histone H3 (monomethylated Lys18)

AS16 3181

詳情

H3K27ac | Histone H3 acetylated lysine 27 (ChIP grade)

AS16 3195

擬南芥、人、小鼠、大鼠

詳情

H3K27me3 | Histone H3, trimethylated lysine 27 (H3K27me3)

AS16 3193

擬南芥、人、楊樹、玉米等

詳情

H3K37me1 | Histone H3 (Monomethylated Lys37)

AS16 3186

詳情

H3K4me3 | Histone H3, trimethylated lysine 4

AS16 3190

擬南芥、人

詳情

H3K56me1 | Histone H3 (monomethylated Lys56)

AS16 3187

詳情

H3K9ac | Histone H3, acetylated lysine 9

AS16 3198

擬南芥、人等

詳情

H3K9me2 | Histone H3 dimethylated lysine 9

AS16 3194

人、番茄

詳情

H3R2me1 | Histone H3 (monomethylated Arg2)

AS16 3167

秀麗隱桿線蟲、人

詳情

H3S10p | Histone H3 (p Ser10) (affinity purified)

AS16 3635

詳情

注:產(chǎn)品名稱命名方式以組蛋白名稱開始,如H3;單一字母的氨基酸簡稱,如K代表賴氨酸,以及在蛋白質(zhì)的位置;修飾的種類,Me即甲基化、P即磷酸化、Ac即乙酰化、Ub即泛素化。


為滿足廣大表觀遺傳學(xué)研究方向客戶的需求,
西美杰聯(lián)合專業(yè)抗體品牌Agrisera推出表觀遺傳學(xué)相關(guān)抗體促銷活動!
活動內(nèi)容如下:

活動時間:即日起至6月30日

活動對象僅限終端客戶參加

促銷規(guī)則:促銷產(chǎn)品限時“7折”特惠

促銷產(chǎn)品除上述小編列舉的組蛋白表觀遺傳修飾抗體外,更有50多種表觀遺傳學(xué)相關(guān)抗體正在進行促銷,請見以下促銷產(chǎn)品清單

產(chǎn)品名稱

產(chǎn)品貨號

5-fC | 5-formylcytosine

AS16 3165

5-hmC | 5-hydroxymethylcytosine (monoclonal)

AS16 3164

5-hmC | 5-hydroxymethylcytosine (polyclonal)

AS16 3166

5-mC | 5-methylcystosine (monclonal antibody for MeDIP/IF)

AS16 3162

5-mC | 5-methylcystosine (monclonal)

AS16 3161

5-mC | 5-methylcystosine (monclonal, clone 33D3)

AS16 3163

Acetylated lysine (25 μl, clone 7F8)

AS10 707-25

Acetylated Lysine (polyclonal)

AS15 3018

Acetylated Lysine, ALP conjugated

AS15 3019

Acetylated Lysine, FITC conjugated

AS15 3020

H2A.XS139p | H2A.X phosphorylated serine 139

AS16 3199

H3 | Histone 3 core | (monoclonal)

AS16 3197

H3K18me1 | Histone H3 (monomethylated Lys18)

AS16 3181

H3K18me2 | Histone H3 (dimethylated Lys18)

AS16 3182

H3K18me3 | Histone H3 (trimethylated Lys18)

AS16 3183

H3K27ac | Histone H3 acetylated lysine 27 (ChIP grade)

AS16 3195

H3K27me3 | Histone H3, trimethylated lysine 27 (H3K27me3)

AS16 3193

H3K27me3S28p | Histone H3 (trimethylated Lys27, p Ser28)

AS16 3184

H3K36me3 | Histone H3 trimethylated lysine 36 (ChIP grade)

AS16 3196

H3K37me1 | Histone H3 (Monomethylated Lys37)

AS16 3186

H3K4me1T6p | Histone H3 (monomethylated Lys4, p Thr6)

AS16 3171

H3K4me3 | Histone H3, trimethylated lysine 4 (H3K4me3)

AS16 3190

H3K4me3 | Histone H3, trimethylated lysine 4 (H3K4me3) (10 μg)

AS16 3190-10

H3K4me3T6p | H3 (trimethylated Lys4, p Thr6)

AS16 3172

H3K56me1 | Histone H3 (monomethylated Lys56)

AS16 3187

H3K56me3 | Histone H3 (trimethylated Lys56)

AS16 3188

H3K9ac | Histone H3, acetylated lysine 9

AS16 3198

H3K9me2 | Histone H3 dimethylated lysine 9

AS16 3194

H3R17me2(asym) | Histone H3 (asym-dimethyl Arg17)

AS16 3180

H3R2me1 | Histone H3 (monomethylated Arg2)

AS16 3167

H3R2me2(sym)K4me2 | Histone H3 (sym-dimethylated Arg2, dimethyl Lys4)

AS16 3185

H3R8me2(asym) | Histone H3 (asym-dimethylated Arg8)

AS16 3177

H3R8me2(sym) | H3 Histone 3 (sym-dimethylated Arg8)

AS16 3178

H3S10p | Histone H3 (p Ser10) (affinity purified)

AS16 3635

H3S10p | Histone H3 (p Ser10) (affinity purified, 10 μl)

AS16 3635-10

H3S10p | Histone H3 (p Ser10) (serum)

AS16 3636

H3S10pT11p | Histone H3 (p Ser10, p Thr11)

AS16 3179

H3T3pK4ac | Histone H3 (ac Lys4, p Thr3)

AS16 3170

H3T3pK4me1 | Histone H3 (p Thr3, monomethylated Lys4)

AS16 3168

H3T3pK4me2 | Histone H3 (dimethylated Lys4, p Thr3)

AS16 3169

H3T6p |  Histone H3 (p Thr6)

AS16 3173

H3T6pK9me1 | Histone H3  methylated at Lys9 (K9)

AS16 3174

H3T6pK9me2 | Histone H3 (dimethylated Lys9, p Thr6)

AS16 3175

H3T6pK9me3 | Histone H3 (trimethylated Lys9, p Thr6)

AS16 3176

H4K16ac | Histone H4 (ac Lys16)

AS16 3189

m6A | N6-methyladenosine (monoclonal)

AS17 4120

m6A | N6-methyladenosine (polyclonal)

AS17 4121

Methylated Lysine

AS15 3021

Methylated Lysine, APC conjugated

AS15 3022

Methylated Lysine, FITC conjugated

AS15 3023

 

 

西美杰做為Agrisera中國區(qū)代理為廣大客戶提供經(jīng)過驗證的高質(zhì)量抗體,優(yōu)質(zhì)的售前咨詢服務(wù)以及良好的抗體售后支持。此外西美杰代理的Lifespan、Mybiosource一抗、檢測試劑盒以及SeraCare(KPL)二抗、底物全方位助力于科學(xué)研究實驗。


 

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